Nicotinamide Riboside 250

250mg (30 caps)
1 capsule 1-2x daily or as directed.
Allergens: Does not contain corn, dairy, gluten, soy, wheat or yeast.

• Nicotinamide Riboside (NR) is a very unique member of the vitamin B3 family.
• The body converts NR into Nicotinamide Adenine Dinucleotide (NAD+), an essential molecule found in every living cell.
• It is essential to every cell but especially to those with mitochondria.
• This is the first and only commercially available form of nicotinamide riboside, as patented NIAGEN® from Chromadex.
• The first human study of NR was published in 2016 and proved NR increases NAD+ levels in adults.
• There are 14 registered clinical trials to date exploring the potential health benefits of NR supplementation.
• This material is considered GRAS.
• Pre-clinical research has demonstrated that supplementing with NR not only safely boosts NAD+, but also enhances the
• body’s production of NAD+ to a greater degree than all other forms of vitamin B3.

• Nicotinamide riboside (NR) has been documented to help replenish cellular NAD+ and in the process:
  • Promote sirtuin (SIRT1 and SIRT3) gene activation
  • Enhance growth and efficiency of mitochondria – supporting energy levels and physical performance
  • Favourably modulate metabolism
  • Contribute to neuronal health – supporting cognitive function during aging
  • Promote insulin sensitivity – supporting healthy blood sugar levels in those within the normal range
• NAD+ is as essential to our cells as food, water and oxygen is to us and NAD+ enables cells to convert food into energy.
• NAD+ is the communication molecule between the cell nucleus and the mitochondria.
• If NAD+ levels are low, then communication may be impaired and mitochondria dysfunction may result.
• Boosting NAD+ levels promote cellular metabolism, mitochondrial function and energy production.
• NAD+ levels are highest at birth and decreases dramatically with age, and poor dietary habits and a sedentary lifestyle deplete
• NAD+ levels.
• When our NAD+ levels are low, cells don’t function optimally.
• NAD+ plays an essential role in regulating genes that control aging.
• NAD+ is a key component of the citric acid cycle and the electron transport chain, both involved in mitochondrial production of ATP for energy.
• As NAD+ is a rate-limiting co-substrate for the sirtuin enzymes, its modulation is emerging as a valuable tool to regulate sirtuin function and, consequently, oxidative metabolism.
• NR supports tissues that heavily rely on the mitochondria for energy: the nervous system, the liver, the heart and muscles.